Journal article

Nikolai N. Anichkov and his theory of atherosclerosis.

Igor E Konstantinov, Nicolai Mejevoi, Nikolai M Anichkov

Texas Heart Institute Journal | Published : 2006


Nikolai N. Anichkov (1885-1964) first demonstrated the role of cholesterol in the development of atherosclerosis. His classic experiments in 1913 paved the way to our current understanding of the role of cholesterol in cardiovascular disease. Anichkov's research is often cited among the greatest discoveries of the 20th century; however, little is known about Anichkov and his team. Herein, we give a detailed historical account of Anichkov's work, his personality, his research team, and their pioneering effort.