Journal article

Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors

Michal Blaszczyk, Nicholas J Harmer, Dimitri Y Chirgadze, David B Ascher, Tom L Blundell

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2015

Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by Wellcome Trust


Funding Acknowledgements

D.B.A is the recipient of a C. J. Martin Research Fellowship from the National Health and Medical Research Council of Australia (APP1072476). TLB and MB receive funding from the Gates Foundation, and T.L.B. and D.Y.C. from The Wellcome Trust (093167) for facilities and support. D.Y.C. is also supported by the Crystallographic X-ray Facility, Department of Biochemistry, University of Cambridge. We thank Ermanno Gherardi for many contributions to the experiments and to our thinking on the Met receptor structure and activation over the years.