Journal article

Genomic resources for a unique, low-virulence Babesia taxon from China

Guiquan Guan, Pasi K Korhonen, Neil D Young, Anson V Koehler, Tao Wang, Youquan Li, Zhijie Liu, Jianxun Luo, Hong Yin, Robin B Gasser

PARASITES & VECTORS | BMC | Published : 2016

Abstract

BACKGROUND: Babesiosis is a socioeconomically important tick-borne disease of animals (including humans) caused by haemoprotozoan parasites. The severity of babesiosis relates to host and parasite factors, particularly virulence/pathogenicity. Although Babesia bovis is a particularly pathogenic species of cattle, there are species of Babesia of ruminants that have limited pathogenicity. For instance, the operational taxonomic unit Babesia sp. Xinjiang (abbreviated here as Bx) of sheep from China is substantially less virulent/pathogenic than B. bovis is in cattle. Although the reason for this distinctiveness is presently unknown, it is possible that Bx has a reduced ability to adhere to cell..

View full abstract

Grants

Awarded by PiroVac of China


Awarded by NSFC of China


Awarded by FRIP of China


Awarded by NBCIS of China


Awarded by Victorian Life Sciences Computation Initiative (VLSCI) grant on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government


Awarded by State Key Laboratory of Veterinary Etiological Biology Project, China


Funding Acknowledgements

This project was partially funded by the the PiroVac (KBBE-3-245145; H.Y.), NSFC (31072130; G.G.), ASTIP, FRIP (2014ZL010), CAAS (H.Y.) and NBCIS (CARS-38; H.Y.) of China and the Australian Research Council (ARC) (R.B.G.); it was also supported by a Victorian Life Sciences Computation Initiative (VLSCI) grant (VR0007; R.B.G.) on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government. Other support from the State Key Laboratory of Veterinary Etiological Biology Project, China (SKLVEB2008ZZKT019; H.Y), the Australian Academy of Science, Alexander von Humboldt Foundation and Melbourne Water Corporation is gratefully acknowledged.