Journal article

Muscle-specific deletion of SOCS3 increases the early inflammatory response but does not affect regeneration after myotoxic injury

Kristy Swiderski, Savant S Thakur, Timur Naim, Jennifer Trieu, Annabel Chee, David I Stapleton, Rene Koopman, Gordon S Lynch

SKELETAL MUSCLE | BIOMED CENTRAL LTD | Published : 2016

DOI: 10.1186/s13395-016-0108-4

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Related Projects (1)

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Role of SOCS3 in defective muscle repair during ageing

Old muscles are slower and weaker than young muscles, they are injured more easily and they repair less successfully. This proposal investig..

Grants

Awarded by Australian Research Council (ARC)

Funding Acknowledgements

This work was supported by the Australian Research Council (ARC; DP120101494). KS was supported by an Early Career Fellowship from the National Health and Medical Research Council (NH&MRC) of Australia.

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Keywords

Life Sciences & Biomedicine
Cytokines
Stat3 Transcription Factor
Science & Technology
Myoblasts, Skeletal
Muscle
Signal Transduction
Cell Biology
Mice, Knockout
Embryonic Stem-Cells
Skeletal-Muscle
Mck
Growth-Factor-I
Male
Cytokine Signaling 3
Macrophages
Mechanisms
Regeneration
Repair
Animals
Cells, Cultured
Elapid Venoms
Inflammation
Female
Janus Kinases
Socs3
Stat3
Muscle Fibers, Skeletal
Messenger-Rna
Physiological Negative Regulator
Myositis
Suppressor of Cytokine Signaling 3 Protein
Stat1 Transcription Factor
Mice