Quantitative Analysis of Iris Changes After Physiologic and Pharmacologic Mydriasis in a Rural Chinese Population
Ye Zhang, Si Zhen Li, Lei Li, Ming Guang He, Ravi Thomas, Ning Li Wang
Investigative Opthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2014
PURPOSE: To estimate and compare the change in iris cross-sectional area (IA) and iris volume (IV) following physiologic and pharmacologic pupil dilation in primary angle closure suspects (PACS) and normal subjects. METHODS: Anterior segment-optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were obtained on 186 PACS and 224 normal subjects examined during the 5-year follow-up of the Handan Eye Study. Iris cross-sectional area, IV, and other biometric parameters calculated using the Zhongshan angle assessment program in the right eyes of all subjects were analyzed. RESULTS: The mean IA and IV decreased in dark compared with light and after..View full abstract
Awarded by Ministry of Health of the People's Republic of China
Supported by the Research Special Fund of the Ministry of Health of the People's Republic of China, Grant 201002019.