Journal article

Quantitative Analysis of Iris Changes After Physiologic and Pharmacologic Mydriasis in a Rural Chinese Population

Ye Zhang, Si Zhen Li, Lei Li, Ming Guang He, Ravi Thomas, Ning Li Wang

Investigative Opthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2014

Abstract

PURPOSE: To estimate and compare the change in iris cross-sectional area (IA) and iris volume (IV) following physiologic and pharmacologic pupil dilation in primary angle closure suspects (PACS) and normal subjects. METHODS: Anterior segment-optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were obtained on 186 PACS and 224 normal subjects examined during the 5-year follow-up of the Handan Eye Study. Iris cross-sectional area, IV, and other biometric parameters calculated using the Zhongshan angle assessment program in the right eyes of all subjects were analyzed. RESULTS: The mean IA and IV decreased in dark compared with light and after..

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University of Melbourne Researchers