Variations in Iris Volume with Physiologic Mydriasis in Subtypes of Primary Angle Closure Glaucoma
Arun Narayanaswamy, Ce Zheng, Shamira A Perera, Hla M Htoon, David S Friedman, Tin A Tun, Mingguang He, Mani Baskaran, Tin Aung
Investigative Ophthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2013
PURPOSE: To compare the changes in iris volume with pupil dilation using anterior segment optical coherence tomography (AS-OCT) in eyes of subjects with different subtypes of primary angle closure. METHODS: This prospective study examined 44 fellow eyes (FA group) of subjects with previous acute primary angle closure (APAC), and 56 subjects (AC group) with chronic primary angle closure and/or primary angle closure glaucoma. All participants underwent gonioscopy and AS-OCT imaging. The iris volume, iris cross-sectional area, and pupil diameter were measured with custom semiautomated software. The main outcome variable analyzed was mean change in iris volume between light and dark conditions i..View full abstract
Supported in part by grants from the National Medical Research Council, Singapore and the National Research Foundation, Singapore.