Journal article

Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs

JB Baell, DCS Huang

Biochemical Pharmacology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2002

DOI: 10.1016/S0006-2952(02)01148-6

University of Melbourne Researchers

Grants

Awarded by NCI NIH HHS

Awarded by NATIONAL CANCER INSTITUTE

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Keywords

Models, Molecular
Humans
Deficient Mice
Protein Structure, Tertiary
Helical Peptides
Programmed Cell-Death
Amino Acid Sequence
Molecular Sequence Data
Induce Apoptosis
Small-Molecule Inhibitors
Life Sciences & Biomedicine
Sequence Homology, Amino Acid
Polycystic Kidney
Science & Technology
Drug Design
Proto-Oncogene Proteins C-Bcl-2
Bh3 Domain
Molecular Mimicry
Cancer
Bh3
Apoptosis
Cytochrome-C
Mitochondrial-Membrane
Pharmacology & Pharmacy
Bh3-Only Proteins
Signal Transduction
Cells, Cultured
Animals
Bcl-2