Novel bilayer bacterial nanocellulose scaffold supports neocartilage formation in vitro and in vivo
Hector Martinez Avila, Eva-Maria Feldmann, Mieke M Pleumeekers, Luc Nimeskern, Willy Kuo, Willem C de Jong, Silke Schwarz, Ralph Mueller, Jeanine Hendriks, Nicole Rotter, Gerjo JVM van Osch, Kathryn S Stok, Paul Gatenholm
Biomaterials | ELSEVIER SCI LTD | Published : 2015
Awarded by Swedish Research Council
Awarded by Federal Ministry of Education and Research
Awarded by SenterNovem
Awarded by Swiss National Science Foundation
This study was performed within the framework of EuroNanoMed (EAREG-406340-131009/1) and was supported by the Swedish Research Council (2009-7838), Federal Ministry of Education and Research (13N11076), SenterNovem (ENM09001) and the Swiss National Science Foundation (NRP63). The authors acknowledge Dr. Annette Jork and Cell Med AG (Alzenau, Germany) for providing medical grade alginate; Athanasios Mantas and Anders Martensson at Chalmers University of Technology (Gothenburg, Sweden) for assistance with scaffold production and FTIR analysis, respectively; and Priscila Martinez Avila at The University of Texas at Arlington for helping with statistical analysis. The antibody used for immunohistochemical type II collagen detection (II-II6B3) was obtained from the Developmental Studies Hybridoma Bank, created by the NICHD of the NIH and maintained at the University of Iowa, Department of Biology, Iowa City, IA 52242, USA.