Journal article

Frequency and predictors of the lupus low disease activity state in a multi-national and multi-ethnic cohort

V Golder, R Kandane-Rathnayake, AYB Hoi, M Huq, W Louthrenoo, Y An, ZG Li, SF Luo, S Sockalingam, CS Lau, AL Lee, MY Mok, A Lateef, K Franklyn, S Morton, STV Navarra, L Zamora, YJ Wu, L Hamijoyo, M Chan Show all

Arthritis Research and Therapy | BIOMED CENTRAL LTD | Published : 2016

Abstract

Background: Systemic lupus erythematosus (SLE) is a chronic heterogeneous disease with considerable burden from disease activity and damage. A novel clinical treatment target in the form of the lupus low disease activity state (LLDAS) has been recently reported, with retrospective validation showing that time spent in LLDAS translates to reduced damage accrual. The objectives of this study were to describe the frequency and identify the predictors of attaining LLDAS in a large multinational cohort of patients with SLE. Methods: Data were collected at the recruitment visit in patients with SLE enrolled in a longitudinal study in nine countries. Data were analysed cross-sectionally against the..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

The Asia-Pacific Lupus Collaboration receives project support grants from GlaxoSmithKline, UCB and Janssen. Dr Golder holds a postgraduate scholarship from the National Health and Medical Research Council (NHMRC, APP1093545), Australia. Dr Nikpour holds an NHMRC research fellowship (APP1071735).