Journal article
Anyplex II HPV28 detection and Anyplex II HPV HR detection assays are highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities
AM Cornall, M Poljak, SM Garland, S Phillips, JH Tan, DA Machalek, MA Quinn, SN Tabrizi
European Journal of Clinical Microbiology and Infectious Diseases | SPRINGER | Published : 2017
Abstract
Purpose: to evaluate the performance of Anyplex II HPV28 and HPV HR Detection assays against the EuroArray HPV, Cobas 4800 HPV (Cobas), HPV Amplicor (Amp), Linear Array HPV (LA) and Hybrid Capture 2 (HC2) in detection of high-risk HPV (HR-HPV) from liquid-based cervical cytology samples. Methods: cervical specimens from 404 women undergoing management of high-grade cytological abnormality were evaluated by Anyplex II HPV28 and HPV HR Detection assays for detection of HR-HPV genotypes and prediction of histologically-confirmed cervical intraepithelial neoplasia grade 2 or higher (≥CIN2). The results were compared to EuroArray, HC2, Cobas, Amp, and LA. Results: specimens were evaluated from 40..
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Funding Acknowledgements
Seegene Inc. supplied the detection kits required for this study. Seegene did not contribute to the design of the study, interpretation of results, or preparation of the manuscript. A member of the Seegene academic team was given the opportunity to comment on technical accuracy of the manuscript related to use of the assay.