Journal article
Submicroscopic and asymptomatic plasmodium parasitaemia associated with significant risk of anaemia in Papua, Indonesia
Z Pava, FH Burdam, I Handayuni, L Trianty, RAS Utami, YK Tirta, E Kenangalem, D Lampah, A Kusuma, G Wirjanata, S Kho, JA Simpson, S Auburn, NM Douglas, R Noviyanti, NM Anstey, JR Poespoprodjo, J Marfurt, RN Price
Plos One | PUBLIC LIBRARY SCIENCE | Published : 2016
Abstract
Submicroscopic Plasmodium infections are an important parasite reservoir, but their clinical relevance is poorly defined. A cross-sectional household survey was conducted in southern Papua, Indonesia, using cluster random sampling. Data were recorded using a standardized questionnaire. Blood samples were collected for haemoglobin measurement. Plasmodium parasitaemia was determined by blood film microscopy and PCR. Between April and July 2013, 800 households and 2,830 individuals were surveyed. Peripheral parasitaemia was detected in 37.7% (968/2,567) of individuals, 36.8% (357) of whom were identified by blood film examination. Overall the prevalence of P. falciparum parasitaemia was 15.4% (..
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Awarded by Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Funding Acknowledgements
The study was supported by the Wellcome Trust (Senior Fellowship in Clinical Science awarded to RNP - 091625) and Fellowships to: JRP (Wellcome Trust - 099875), JM (The Swiss National Science Foundation - PA00P3-139723/1), ZP (Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnologia Francisco Jose de Caldas, Colciencias - 512-2010) and NMA (National Health and Medical Research Council (NHMRC) of Australia - 1042072). The Timika Research Facility and Papuan Health and Community Development Foundation were supported by DFAT (Australian Department of Foreign Affairs and Trade) and the NHMRC (Program Grant 1037304).