MEASUREMENT OF ROTAVIRUS-NEUTRALIZING COPROANTIBODY IN CHILDREN BY FLUORESCENT FOCUS REDUCTION ASSAY
BS COULSON, PJ MASENDYCZ
Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 1990
A fluorescent focus reduction assay suitable for the measurement of rotavirus-neutralizing antibodies in the feces of children was developed. Of 408 stools tested, 7% showed false-positive neutralization, and the number of rotavirus serotypes neutralized by a fecal extract was proportional to the levels of antirotaviral immunoglobulin A in the extract.