Journal article

CLASSIFICATION AND NOMENCLATURE OF SOMATOSTATIN RECEPTORS

D HOYER, GI BELL, M BERELOWITZ, J EPELBAUM, W FENIUK, PPA HUMPHREY, AM OCARROLL, YC PATEL, A SCHONBRUNN, JE TAYLOR, T REISINE

Trends in Pharmacological Sciences | ELSEVIER SCI LTD | Published : 1995

Abstract

There is considerable controversy about the classification and nomenclature of somatostatin receptors. To date, five distinct receptor genes have been cloned and named chronologically according to their respective publication dates, but two were unfortunately given the same appellation (SSTR4). Consensually, a nomenclature for the recombinant receptors has been agreed according to IUPHAR guidelines (sst1, sst2, sst3, sst4, and sst5). However, a more informative classification is to be preferred for the future, employing all classification criteria in an integrated scheme. It is already apparent that the five recombinant receptors fall into two classes or groups, on the basis of not only stru..

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University of Melbourne Researchers