Intracellular plasma proteins in human fetal choroid plexus during development. II. The distribution of prealbumin, albumin, alpha-fetoprotein, transferrin, IgG, IgA, IgM, and alpha 1-antitrypsin.

Abstract

Individual choroid plexuses of human fetal brain at different developmental stages were investigated by an indirect immunoperoxidase technique. The number and distribution of prealbumin-, albumin-, alpha-fetoprotein-, transferrin-, IgG-, IgA-, IgM- and alpha 1-antitrypsin-containing choroid plexus epithelial cells were recorded. The distribution of prealbumin in choroid plexus epithelial cells differed from that of other plasma proteins identified in these cells. Prealbumin was present in more than 90% of the cells at all ages examined in contrast to albumin, alpha-fetoprotein, transferrin and IgG, which were found in less than 40% of the cells, and this proportion declined later in gestatio..