Journal article

Biosynthesis and Mass Spectrometric Imaging of Tolaasin, the Virulence Factor of Brown Blotch Mushroom Disease

Kirstin Scherlach, Gerald Lackner, Katharina Graupner, Sacha Pidot, Tom Bretschneider, Christian Hertweck

ChemBioChem | WILEY-V C H VERLAG GMBH | Published : 2013

Abstract

Killing them softly. The molecular basis for the biosynthesis of tolaasin, the Pseudomonas tolaasii-derived causative agent of mushroom (Agaricus bisporus) soft rot, was revealed by genome mining and analysis of the NRPS genes. Production of the toxic lipopeptides during infection was confirmed by imaging mass spectrometry. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

University of Melbourne Researchers