Journal article

The Temporal Evolution and Global Spread of Cauliflower mosaic virus, a Plant Pararetrovirus

Ryosuke Yasaka, Huy D Nguyen, Simon YW Ho, Sebastian Duchene, Savas Korkmaz, Nikolaos Katis, Hideki Takahashi, Adrian J Gibbs, Kazusato Ohshima

PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2014


Cauliflower mosaic virus (CaMV) is a plant pararetrovirus with a double-stranded DNA genome. It is the type member of the genus Caulimovirus in the family Caulimoviridae. CaMV is transmitted by sap inoculation and in nature by aphids in a semi-persistent manner. To investigate the patterns and timescale of CaMV migration and evolution, we sequenced and analyzed the genomes of 67 isolates of CaMV collected mostly in Greece, Iran, Turkey, and Japan together with nine published sequences. We identified the open-reading frames (ORFs) in the genomes and inferred their phylogeny. After removing recombinant sequences, we estimated the substitution rates, divergence times, and phylogeographic patter..

View full abstract


Awarded by Japan Society for the Promotion of Science (JSPS) KAKENHI

Awarded by JSPS

Awarded by Grants-in-Aid for Scientific Research

Funding Acknowledgements

This work was in part funded by Saga University, and supported by Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Numbers 18405022 and 24405026. This work was in part supported by JSPS Postdoctoral Fellowships for Foreign Researchers Grant Number 21.09320 to KO and S. Farzadfar (Saga University). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.