Journal article
Prediagnostic alcohol consumption and colorectal cancer survival: The Colon Cancer Family Registry
AI Phipps, JR Robinson, PT Campbell, AK Win, JC Figueiredo, NM Lindor, PA Newcomb
Cancer | WILEY | Published : 2017
DOI: 10.1002/cncr.30446
Abstract
BACKGROUND: Although previous studies have noted an increased risk of colorectal cancer (CRC) among moderate to heavy alcohol consumers in comparison with nondrinkers, the relation between alcohol consumption and CRC survival remains unclear. METHODS: Cases of incident invasive CRC diagnosed between 1997 and 2007 were identified via population-based cancer registries at 4 study sites in the Colon Cancer Family Registry. Study participants completed a risk-factor questionnaire on prediagnostic behaviors, including wine, beer, and liquor consumption, at the baseline. Prospective follow-up for survival was conducted for 4966 CRC cases. Cox regression was used to compare nondrinkers with individ..
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Awarded by National Institutes of Health
Funding Acknowledgements
This work was supported by grant UM1CA167551 from the National Cancer Institute (National Institutes of Health) and through cooperative agreements with members of the Colon Cancer Family Registry and principal investigators. Centers contributing to this analysis include the Australasian Colorectal Cancer Family Registry (U01/U24CA097735), the Mayo Clinic Cooperative Family Registry for Colon Cancer Studies (U01/U24CA074800), the Ontario Familial Colorectal Cancer Registry (U01/U24CA074783), and the Seattle Colorectal Cancer Family Registry (U01/U24CA074794). This work was also supported by National Cancer Institute grants K07CA172298 (to Amanda I. Phipps) and K05CA152715 (to Polly A. Newcomb) and National Institute of Environmental Health Sciences (National Institutes of Health) grant T32ES015459 (to Jamaica R. Robinson). The contents of this article do not necessarily reflect the views or policies of the National Institutes of Health or any of the collaborating centers in the Colon Cancer Family Registry, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government or the Colon Cancer Family Registry.