Journal article

Comparative transcriptomic analyses of male and female adult Toxocara canis

Rong-Qiong Zhou, Guang-Xu Ma, Pasi K Korhonen, Yong-Li Luo, Hong-Hong Zhu, Yong-Fang Luo, Robin B Gasser, Qing-You Xia

GENE | ELSEVIER SCIENCE BV | Published : 2017


Toxocariasis is an important, neglected zoonosis caused mainly by Toxocara canis. Although our knowledge of helminth molecular biology is improving through completed draft genome projects, there is limited detailed information on the molecular biology of Toxocara species. Here, transcriptomic sequencing of male and female adult T. canis and comparative analyses were conducted. For each sex, two-thirds (66-67%) of quality-filtered reads mapped to the gene set of T. canis, and at least five reads mapped to each of 16,196 (87.1%) of all 18,596 genes, and 321 genes were specifically transcribed in female and 1467 in male T. canis. Genes differentially transcribed between the two sexes were ident..

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Awarded by National Basic Research Program of China

Awarded by National Natural Science Foundation of China

Funding Acknowledgements

This work was funded by the National Basic Research Program of China (no. 2012CB114600), the National Natural Science Foundation of China (no. 31172313) and the Youth Fund Project (2015) of Southwest University Rongchang Campus. RBG's research is supported by the Australian Research Council (ARC), the National Health and Medical Research Council (NHMRC), the Victorian Life Sciences Computation Initiative, Melbourne Water Corporation, YourGene Biosciences - Taiwan and the University of Melbourne (BIP). P.K.K. is an NHMRC Early Career Research Fellow (ECRF). We thank BGI-Shenzhen (China) for sequencing service.