Journal article

Full Genome Analysis of Australian Infectious Bronchitis Viruses Suggests Frequent Recombination Events between Vaccine Strains and Multiple Phylogenetically Distant Avian Coronaviruses of Unknown Origin

JA Quinteros, SW Lee, PF Markham, AH Noormohammadi, CA Hartley, AR Legione, MJC Coppo, PK Vaz, GF Browning

Veterinary Microbiology | Elsevier | Published : 2016

Abstract

Australian strains of infectious bronchitis virus (IBV) have been evolving independently for many years, with control achieved by vaccination with local attenuated strains. Previous studies have documented the emergence of recombinants over the last 20 years, with the most recent one, Ck/Aus/N1/08, detected in 2008. These recombinants did not appear to be controlled by the vaccines currently in use. In this study we sequenced the complete genomes of three emergent Australian strains of IBV (IBV/Ck/Aus/N1/88, IBV/Ck/Aus/N1/03 and IBV/Ck/Aus/N1/08) and a previously incompletely characterised vaccine strain, IBV/Ck/Aus/Armidale, and compared them to the genome of the vaccine strain VicS. We d..

View full abstract