Epidemiology and etiology of influenza-like-illness in households in Vietnam; it's not all about the kids!
Ngoc Thi Nguyen Diep, Quynh Mai Le, Juliet E Bryant, Le Khanh Hang Nguyen, Nguyen Minh Hoa Le, Behzad Nadjm, Quang Thai Pham, Nhu Duong Tran, Duc Anh Dang, Peter Horby, H Rogier van Doorn, Heiman FL Wertheim, Annette Fox
JOURNAL OF CLINICAL VIROLOGY | ELSEVIER SCIENCE BV | Published : 2016
BACKGROUND: Household studies provide opportunities to understand influenza-like-illness (ILI) transmission, but data from (sub)tropical developing countries are scarce. OBJECTIVE: To determine the viral etiology and epidemiology of ILI in households. STUDY DESIGN: ILI was detected by active case finding amongst a cohort of 263 northern Vietnam households between 2008 and 2013. Health workers collected nose and throat swabs for virus detection by multiplex real-time RT-PCR. RESULTS: ILI was detected at least once in 219 (23.7%) of 945 household members. 271 (62.3%) of 435 nose/throat swabs were positive for at least one of the 15 viruses tested. Six viruses predominated amongst positive swab..View full abstract
Awarded by Wellcome Trust UK
Awarded by European Union FP7 project "European Management Platform for Emerging and Re-emerging Infectious Disease Entities (EMPERIE)"
This work was supported by the Wellcome Trust UK (grants 081613/Z/06/Z; 077078/Z/05/Z). AF was supported by the European Union FP7 project "European Management Platform for Emerging and Re-emerging Infectious Disease Entities (EMPERIE)" (no. 223498).