Journal article

Lack of association between duration of breast-feeding or introduction of cow's milk and development of islet autoimmunity

JJ Couper, C Steele, S Beresford, T Powell, K McCaul, A Pollard, S Gellert, B Tait, LC Harrison, PG Colman

Diabetes | AMER DIABETES ASSOC | Published : 1999


The hypothesis that early exposure to cow's milk or lack of breast-feeding predisposes to type 1 diabetes remains controversial. We aimed to determine prospectively the relationship of, first, duration of exclusive breast-feeding and total duration of breast-feeding, and second, introduction of cow's milk protein as infant formula, cow's milk, or dairy products, to the development of islet antibodies in early life. Some 317 children with a first-degree relative with type 1 diabetes were followed prospectively from birth for 29 months (4-73). Mothers kept a home diary and answered infant feeding questionnaires at 6-month intervals. No systematic feeding advice was given. Insulin autoantibodie..

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