Journal article

Mammographic density assessed on paired raw and processed digital images and on paired screen-film and digital images across three mammography systems

Anya Burton, Graham Byrnes, Jennifer Stone, Rulla M Tamimi, John Heine, Celine Vachon, Vahit Ozmen, Ana Pereira, Maria Luisa Garmendia, Christopher Scott, John H Hipwell, Caroline Dickens, Joachim Schuz, Mustafa Erkin Aribal, Kimberly Bertrand, Ava Kwong, Graham G Giles, John Hopper, Beatriz Perez Gomez, Marina Pollan Show all

BREAST CANCER RESEARCH | BIOMED CENTRAL LTD | Published : 2016

Abstract

BACKGROUND: Inter-women and intra-women comparisons of mammographic density (MD) are needed in research, clinical and screening applications; however, MD measurements are influenced by mammography modality (screen film/digital) and digital image format (raw/processed). We aimed to examine differences in MD assessed on these image types. METHODS: We obtained 1294 pairs of images saved in both raw and processed formats from Hologic and General Electric (GE) direct digital systems and a Fuji computed radiography (CR) system, and 128 screen-film and processed CR-digital pairs from consecutive screening rounds. Four readers performed Cumulus-based MD measurements (n = 3441), with each image pair ..

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Grants

Awarded by US National Cancer Institute at the National Institutes of Health


Awarded by Cancer Research UK


Awarded by National Breast Cancer Foundation


Awarded by NATIONAL CANCER INSTITUTE


Funding Acknowledgements

This work was supported by the US National Cancer Institute at the National Institutes of Health (R03CA167771) and by the International Agency for Research on Cancer.