Journal article

SENSITIVITY OF SKIN SNIPS IN THE DIAGNOSIS OF ONCHOCERCIASIS

HR TAYLOR, E KEYVANLARIJANI, HS NEWLAND, AT WHITE, BM GREENE

TROPICAL MEDICINE AND PARASITOLOGY | GEORG THIEME VERLAG | Published : 1987

Abstract

To find the optimum number and combination of skin snips for the diagnosis of onchocerciasis, data of six skin snips (two shoulder, two hip, two calf) taken from 776 Liberians aged 12 to 60 years were examined. From these data, proportions of positive skin snips from the hip, or hip and calf areas, for different levels of skin microfilaria density were calculated. These proportions were used in a mathematical model that examined 20 hypothetical populations with different levels of endemicity and skin microfilaria densities. The sensitivity of using two or four snips was then estimated. If only two snips were taken, two hip snips had the highest sensitivity (ranging from 80.7% to 100% accordi..

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