Natural recombination in alphaherpesviruses: Insights into viral evolution through full genome sequencing and sequence analysis
Carlos A Loncoman, Paola K Vaz, Mauricio JC Coppo, Carol A Hartley, Francisco J Morera, Glenn F Browning, Joanne M Devlin
INFECTION GENETICS AND EVOLUTION | ELSEVIER SCIENCE BV | Published : 2017
Recombination in alphaherpesviruses was first described more than sixty years ago. Since then, different techniques have been used to detect recombination in natural (field) and experimental settings. Over the last ten years, next-generation sequencing (NGS) technologies and bioinformatic analyses have greatly increased the accuracy of recombination detection, particularly in field settings, thus contributing greatly to the study of natural alphaherpesvirus recombination in both human and veterinary medicine. Such studies have highlighted the important role that natural recombination plays in the evolution of many alphaherpesviruses. These studies have also shown that recombination can be a ..View full abstract
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Awarded by Australian Research Council
Carlos A Loncoman is supported by the Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT), Chilean Government. This work was supported by the Australian Research Council (FT140101287).