Journal article

Comparative performance of the Kalon and HerpeSelect enzyme-linked immunosorbant assays to determine the prevalence of herpes simplex virus type 2 in Papua New Guinea

Claire E Ryan, Cassey S Simbiken, Paul A Agius, Joyce Allen, Joyce Sauk, Petronia Kaima, Zure Kombati, Peter Siba, John M Kaldor, Andrew Vallely

Sexual Health | CSIRO PUBLISHING | Published : 2014


Background Infection with herpes simplex virus type 2 (HSV-2) is common worldwide and an important risk factor for HIV infection. Aetiological diagnosis of HSV-2 is typically determined with the use of commercially available type-specific enzyme-linked immunosorbent assays (ELISAs). This study aimed to determine the prevalence of HSV-2 among people attending sexual health clinics in the Highlands of Papua New Guinea. The study also aimed to compare the performance of two type-specific ELISA assays, the Kalon and HerpeSelect glycoprotein G2 assays, in this context. Methods: Participants were recruited as part of a longitudinal sexual health study. Participants attended four appointments over ..

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Funding Acknowledgements

We would like to acknowledge all the participants in the longitudinal clinical cohort study. A further acknowledgement needs to be extended to all clinical staff involved in the recruitment, interviewing and testing of patients. The authors (CR, PA) acknowledge the Victorian Department of Innovation and Industry and the Australian National Health and Medical Research Council for institutional infrastructure funding.