Journal article
Body size from birth through adolescence in relation to risk of benign breast disease in young women
CS Berkey, B Rosner, RM Tamimi, WC Willett, M Hickey, A Toriola, AL Frazier, GA Colditz
Breast Cancer Research and Treatment | SPRINGER | Published : 2017
Abstract
Purpose: Body size, from birth throughout adulthood, is associated with breast cancer risk, but few studies have investigated early-life body size and benign breast disease (BBD), a well-established breast cancer risk factor. We consider whether prenatal factors and size at birth, 10, 18 year, and intervening growth, are related to BBD risk. Methods: The Growing Up Today Study includes 9032 females who completed questionnaires annually from 1996 to 2001, then 2003, 2005, 2007, 2010, and 2013. In 1996, their mothers provided pregnancy-related data. From 2005 to 2013, participants (18 year+) reported whether they had ever been diagnosed with biopsy-confirmed BBD (N = 142 cases). Results: Girls..
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Awarded by National Institutes of Health
Funding Acknowledgements
Supported by a Grant from The Breast Cancer Research Foundation (NYC, NY) to Dr. Colditz and by DK046834 from the National Institutes of Health (Bethesda, MD). Dr. Frazier was supported by an award from the American Institute for Cancer Research. Dr. Colditz, who founded GUTS, was supported, in part, by an American Cancer Society Clinical Research Professorship. The authors appreciate the ongoing, since 1996, dedication of our female GUTS participants and their mothers in NHSII.