Journal article

The neuropathology of HIV: A review of the first 10 years

IP Everall, PL Lantos

International Review of Psychiatry | Published : 1991

Abstract

Since the early 1980s there has been an increasing recognition of the importance of involvement of the brain in HIV infection. It is now known that the brain is infected very early on and that cerebral pathology occurs in approximately 90% of the patients who have died of AIDS. This review will portray the evolution of our understanding during the first 10 years of the epidemic of AIDS. Discussion will concentrate on four main areas. First, there is a description of diseases affecting the brain including opportunistic infections, neoplasms, and pathology directly induced by HIV. Secondly, the significance of these neuropathological abnormalities will be explored by correlating them with clin..

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