Spatial data analysis in the quantitative assessment of cerebral white matter pathology on MRI in HIV infection.
RJ Corrigall, WK Chong, M Paley, ID Wilkinson, P Lantos, I Everall
Neuroradiology | Published : 1995
This study was carried out using MRI (proton density--and T2-weighted) on 16 HIV-negative controls, 9 symptom-free HIV-positive patients and 25 with CDC IV HIV disease. The studies from this last group had previously been allocated by a radiologist to the following categories: 8 with focal mass lesions and normal-appearing white matter; 9 with diffuse encephalopathy (high signal on T2-weighted images, affecting most or all of the white matter) and 8 with patchy encephalopathy (high signal affecting only one or two areas within the white matter). Moran's I, a statistic of spatial autocorrelation, was calculated for the grey-scale values of a sampled pixel array from a central white matter reg..View full abstract