Journal article

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE"

Peter Savas, Zhi Ling Teo, Christophe Lefevre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi

PLoS Medicine | PUBLIC LIBRARY SCIENCE | Published : 2016


Awarded by UK Medical Research Council grant (UKMRC)

Awarded by Cancer Research UK

Awarded by UKMRC

Awarded by Wellcome Trust

Awarded by NHMRC Program Grant

Awarded by NovoNordisk Foundation

Awarded by Medical Research Council

Awarded by Novo Nordisk Fonden

Awarded by National Breast Cancer Foundation

Funding Acknowledgements

This work was supported by the National Breast Cancer Foundation (NBCF, of Australia, the Breast Cancer Research Foundation (BCRF,, New York, a UK Medical Research Council grant (UKMRC, MR/FC001169/1), and the Francis Crick Institute (, which receives its core funding from Cancer Research UK (FC001169,, the UKMRC (FC001169,, and the Wellcome Trust (FC001169, PS is supported by National Health and Medical Research Council of Australia (NHMRC,, NBCF, and Cancer Therapeutics CRC ( post-graduate scholarships. The kConFab Clinical Follow-Up Study is supported by the NHMRC, NBCF, Cancer Australia (, and the National Institutes of Health ( kConFab is supported by NBCF, previously the NHMRC, the Cancer Councils of Queensland (, New South Wales (, Victoria (, Tasmania (, and South Australia (, and the Cancer Foundation of Western Australia ( SJD is supported by a NBCF and Victorian Cancer Agency ( Fellowship. TPS is supported by a NHMRC Program Grant (1054618). CS is the Royal Society Napier Research Professor and is funded by Cancer Research UK (TRACERx), the Cancer Research UK Lung Cancer Centre of Excellence (, Stand Up 2 Cancer (SU2C,, the Rosetrees Trust (, NovoNordisk Foundation (ID 16584,, the Prostate Cancer Foundation (, BCRF, and the European Research Council (THESEUS, Support was provided to CS by the National Institute for Health Research (, the University College London Hospitals Biomedical Research Centre (, and the Cancer Research UK University College London Experimental Cancer Medicine Centre ( SL is supported by the John Colebatch Cancer Council of Victoria Clinical Fellowship ( and the NHMRC. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.