Journal article
Cancer Care Coordinators to Improve Tamoxifen Persistence in Breast Cancer: How Heterogeneity in Baseline Prognosis Impacts on Cost-Effectiveness
N Nair, G Kvizhinadze, T Blakely
Value in Health | ELSEVIER SCIENCE INC | Published : 2016
Abstract
Objectives To assess the cost-effectiveness of a cancer care coordinator (CCC) in helping women with estrogen receptor positive (ER+) early breast cancer persist with tamoxifen for 5 years. Methods We investigated the cost-effectiveness of a CCC across eight breast cancer subtypes, defined by progesterone receptor (PR) status, human epidermal growth factor receptor 2 (HER2) status, and local/regional spread. These subtypes range from excellent to poorer prognoses. The CCC helped in improving tamoxifen persistence by providing information, checking-in by phone, and “troubleshooting” concerns. We constructed a Markov macrosimulation model to estimate health gain (in quality-adjusted life-years..
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Funding Acknowledgements
Financial support for this study was provided entirely by a grant (10/248) from the Health Research Council of New Zealand. The funding agreement ensured the authors' independence in designing the study, interpreting the data, and writing and publishing the report.