Interleukin-2 receptor-alpha proximal promoter hypomethylation is associated with multiple sclerosis

J Field; A Fox; MA Jordan; AG Baxter; T Spelman; M Gresle; H Butzkueven; TJ Kilpatrick; JP Rubio

Journal article

Interleukin-2 receptor-alpha proximal promoter hypomethylation is associated with multiple sclerosis

J Field, A Fox, MA Jordan, AG Baxter, T Spelman, M Gresle, H Butzkueven, TJ Kilpatrick, JP Rubio

Genes & Immunity | NATURE PUBLISHING GROUP | Published : 2017

DOI: 10.1038/gene.2016.50

University of Melbourne Researchers

Justin Rubio Author Florey Department of Neuroscience and Mental Health

Trevor Kilpatrick Author Florey Department of Neuroscience and Mental Health

Judith Field Author Anatomy and Physiology

Timothy Spelman Author Surgery - St Vincent's Hospital

Helmut Butzkueven Author Medicine - Royal Melbourne Hospital

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Grants

Awarded by NHMRC

Funding Acknowledgements

We thank all the people with MS and control persons who participated in this study, and are grateful to Jennifer Eckholdt and John Carey for their assistance with the collection of blood samples for this study. This work was supported by NHMRC Project Grants (nos 257518 and 509184) and JF was supported by a Multiple Sclerosis Research Australia Fellowship. This work was also funded by Multiple Sclerosis Research Australia, National Health and Medical Research Council Australia, Lions International and Rebecca L Cooper Foundation. MAJ is supported by an NHMRC/MSRA Betty Cuthbert fellowship. AGB is supported by an Australian National Health and Medical Research Council (NHMRC) Research Fellowship.