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Journal article

Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis

KA Browne, RW Johnstone, DA Jans, JA Trapani

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2000

DOI: 10.1074/jbc.C000622200

University of Melbourne Researchers

Ricky Johnstone's Profile Picture
Ricky Johnstone Author The Sir Peter MacCallum Department of Oncology

Joseph Trapani's Profile Picture
Joseph Trapani Author The Sir Peter MacCallum Department of Oncology

Citation metrics

66Web of Science
73Scopus
71Dimensions

Keywords

Perforin
Ligands
Serine Endopeptidases
Family
Cytosolic Delivery
Contractile Proteins
Two-Hybrid System Techniques
Dependence
Cytoplasm
Binding Sites
Dose-Response Relationship, Drug
Gelsolin
Jurkat Cells
Science & Technology
Cell Membrane
Caspases
Cysteine Proteinase Inhibitors
Tumor Cells, Cultured
Fas Receptor
Biochemistry & Molecular Biology
Gene
Life Sciences & Biomedicine
Cell Survival
Membrane Glycoproteins
Precipitin Tests
Abp-280
Enzyme Inhibitors
Chromium Radioisotopes
Pore Forming Cytotoxic Proteins
T-Lymphocytes, Cytotoxic
Staurosporine
Mediated Apoptosis
Target-Cells
Amino Acid Chloromethyl Ketones
Apoptosis
Dna Fragmentation
Cell Nucleus
Humans
Granzymes
Microfilament Proteins
in Situ Nick-End Labeling
Filamins

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