A highly sensitive SERS-based platform for Zn(II) detection in cellular media

Hongjun Zhuang; Zhenzhen Wang; Xiangchun Zhang; James A Hutchison; Wenfeng Zhu; Zhiyi Yao; Yuliang Zhao; Min Li

Journal article

A highly sensitive SERS-based platform for Zn(II) detection in cellular media

Hongjun Zhuang, Zhenzhen Wang, Xiangchun Zhang, James A Hutchison, Wenfeng Zhu, Zhiyi Yao, Yuliang Zhao, Min Li

Chemical Communications | Royal Society of Chemistry | Published : 2017

DOI: 10.1039/c6cc08541e

Abstract

We report a highly sensitive and selective surface-enhanced Raman scattering (SERS)-based detection of aqueous Zn(II) ions (limit of detection 10−14 M). Spectral changes for a silver nanoparticle-bound Raman reporter upon Zn(II) chelation constitutes the assay, which is applied to drinking water and to measurements of cellular uptake of Zn(II).

University of Melbourne Researchers

James Hutchison Author Chemistry

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Grants

Awarded by National Natural Science Foundation of China

Awarded by National Basic Research Program of China

Awarded by Australian Research Council DECRA scheme

Awarded by Australian Research Council

Funding Acknowledgements

This work was supported in part by the National Natural Science Foundation of China (Grant No. 31671012, 21303208), the National Basic Research Program of China (No. 2015CB932004). This project was also sponsored by the Australian Research Council DECRA scheme (DE130101300) and the Australian Research Council Grant LF 100100117.