LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease
Dean S Griffiths, Juan Li, Mark A Dawson, Matthew WB Trotter, Yi-Han Cheng, Aileen M Smith, William Mansfield, Pentao Liu, Tony Kouzarides, Jennifer Nichols, Andrew J Bannister, Anthony R Green, Berthold Goettgens
Nature Cell Biology | NATURE PUBLISHING GROUP | Published : 2011
Awarded by Medical Research Council
Awarded by National Centre for the Replacement
We gratefully acknowledge the assistance of S. Kinston for technical support, M. Anderson and T. Hamilton for 8-cell-stage injections, K. Griffiths and A. Johnston for assistance with statistics, N. Ivanova for the Nanog shRNA vector, S. Pollard for use of Incucyte, A. Smith for STAT3-null and Nanog-overexpressing ES cells and for helpful discussions and A. Bradley for helpful discussions. Research in the authors' laboratories is supported by Cancer Research UK, Leukaemia and Lymphoma Research, The Leukaemia and Lymphoma Society and Medical Research Council.