Journal article
Prognostic accuracy of the SOFA score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit
EP Raith, AA Udy, M Bailey, S McGloughlin, C MacIsaac, R Bellomo, DV Pilcher
JAMA Journal of the American Medical Association | AMER MEDICAL ASSOC | Published : 2017
Abstract
IMPORTANCE The Sepsis-3 Criteria emphasized the value of a change of 2 or more points in the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score, introduced quick SOFA (qSOFA), and removed the systemic inflammatory response syndrome (SIRS) criteria from the sepsis definition. OBJECTIVE Externally validate and assess the discriminatory capacities of an increase in SOFA score by 2 or more points, 2 or more SIRS criteria, or a qSOFA score of 2 or more points for outcomes among patients who are critically ill with suspected infection. DESIGN, SETTING, AND PARTICIPANTS Retrospective cohort analysis of 184 875 patients with an infection-related primary admission diagnosis in 182 Aust..
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Funding Acknowledgements
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Udy receives salary support from Monash University as an Alfred ICU Monash University practitioner fellow and receives support from the National Health and Medical Research Council of Australia (Early Career Fellowship). Dr Bailey receives salary support from the School of Public Health, Monash University. Dr Pilcher receives salary support from Monash University as an Alfred ICU Monash University practitioner fellow.