Journal article

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Shuo Wei, Shingo Kozono, Lev Kats, Morris Nechama, Wenzong Li, Jlenia Guarnerio, Manli Luo, Mi-Hyeon You, Yandan Yao, Asami Kondo, Hai Hu, Gunes Bozkurt, Nathan J Moerke, Shugeng Cao, Markus Reschke, Chun-Hau Chen, Eduardo M Rego, Francesco Lo-Coco, Lewis C Cantley, Tae Ho Lee Show all

NATURE MEDICINE | NATURE PUBLISHING GROUP | Published : 2015

Grants

Awarded by Susan G. Komen for the Cure postdoctoral fellowship


Awarded by US National Institutes of Health


Awarded by NATIONAL CANCER INSTITUTE


Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE


Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES


Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES


Awarded by NATIONAL INSTITUTE ON DRUG ABUSE


Funding Acknowledgements

We thank W. G. Kaelin Jr., N. Gray, J. Clardy and A. Chakraborty for constructive advice; and H. de The (INSERM) for RAR-alpha, RAR-beta, and RAR-gamma triple-KO MEFs originally generated by P.A. Chambon (Universite de Strasbourg); C. Ng for assistance with immunostaining and T. Garvey for editing the manuscript. S.W. is a recipient of a Susan G. Komen for the Cure postdoctoral fellowship (KG111233). The work is supported by grants from the US National Institutes of Health (R01CA167677, R03DA031663 and R01HL111430 to K.P.L.).