Cryo-EM of the pathogenic VCP variant R155P reveals long-range conformational changes in the D2 ATPase ring

Driss Mountassif; Lucien Fabre; Younes Zaid; Dalia Halawani; Isabelle Rouiller

Journal article

Cryo-EM of the pathogenic VCP variant R155P reveals long-range conformational changes in the D2 ATPase ring

Driss Mountassif, Lucien Fabre, Younes Zaid, Dalia Halawani, Isabelle Rouiller

Biochemical and Biophysical Research Communications | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2015

DOI: 10.1016/j.bbrc.2015.11.003

University of Melbourne Researchers

Isabelle Rouiller Author Biochemistry and Molecular Biology

Grants

Awarded by Canadian Institutes of Health Research (CIHR)

Funding Acknowledgements

This work was supported by operating grants to I.R. from the Canadian Institutes of Health Research (CIHR reference number 86693MOP). I.R. received a CIHR New Investigator award. The Canadian Foundation for Innovation provided infrastructure. The Facility for Electron Microscopy Research at McGill University (FEMR) provided technical support and access to equipment. This work was facilitated by computing resources from CLUMEQ under Compute/Calcul Canada.