Coordinated Rearrangements between Cytoplasmic and Periplasmic Domains of the Membrane Protein Complex ExbB-ExbD of Escherichia coli
Aleksandr Sverzhinsky, Lucien Fabre, Andrew L Cottreau, Damien MP Biot-Pelletier, Sofia Khalil, Mihnea Bostina, Isabelle Rouiller, James W Coulton
Structure | CELL PRESS | Published : 2014
Awarded by Canadian Institutes of Health Research (CIHR)
This work was supported by operating grants to J.W.C. from the Canadian Institutes of Health Research (CIHR reference number 200709MOP-178048-BMA-CFAA-11449) and I.R. (CIHR reference number 86693MOP). I.R. is a CIHR New Investigator. The Groupe d'etude des proteines membranaires (GEPROM), supported by the Fonds de la recherche en santedu Quebec (FRSQ), awarded a Projet Novateur to both principal investigators. A.S. was awarded fellowships from the CREATE program, Cellular Dynamics of Macromolecular Complexes, Natural Sciences and Research Engineering Council (NSERC) of Canada; GEPROM; and the F.C. Harrison and the Rozanis Funds, Department of Microbiology and Immunology, McGill University. L.F. and A.L.C. were awarded fellowships from GEPROM. D.B.-P. received a PGS-M scholarship from NSERC and an international training award from FRSQ. Canada Foundation for Innovation provided infrastructure for the Facility for Electron Microscope Research, McGill University (http://www.medicine.mcgill.ca/femr/home.html). Mass spectrometry services were provided by Marcos Di Falco, Genome Quebec Proteomics Platform. This work was facilitated by computing resources from CLUMEQ under Compute/Calcul Canada. We appreciate laboratory support from Nathalie Croteau and suggestions on the manuscript by B. Cousineau, J.M. Kollman, and J. Kashul. This paper is dedicated to Professor R.G.E. Murray, electron microscopist, who celebrates his 70th year of graduation (1943) from McGill University.