Journal article

Bursts of seizures in long-term recordings of human focal epilepsy

Philippa J Karoly, Ewan S Nurse, Dean R Freestone, Hoameng Ung, Mark J Cook, Ray Boston

EPILEPSIA | WILEY | Published : 2017


OBJECTIVE: We report on temporally clustered seizures detected from continuous long-term ambulatory human electroencephalographic data. The objective was to investigate short-term seizure clustering, which we have termed bursting, and consider implications for patient care, seizure prediction, and evaluating therapies. METHODS: Chronic ambulatory intracranial electroencephalography (EEG) data collected for the purpose of seizure prediction were annotated to identify seizure events. A detection algorithm was used to identify bursts of events. Burst events were compared to nonburst events to evaluate event dispersion, duration and dynamics. RESULTS: Bursts of seizures were present in 6 of 15 s..

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