Journal article

Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases

Charussri Leeyaphan, Jason J Ong, Eric PF Chow, Karolina Dimovski, Fabian YS Kong, Jane S Hocking, Ben Howden, Melanie Bissessor, Christopher K Fairley, Catriona Bradshaw, Timothy Read, Marcus Chen

Sexually Transmitted Diseases | Wolters Kluwer | Published : 2017

Abstract

Background: Treatment for rectal lymphogranuloma venereum where doxycycline 100 mg twice daily for 21 days was used—either alone or together with azithromycin 1 g single dose—resulted in microbiological cure of 97%. These data support doxycycline 100 mg twice daily for 21 days as the preferred treatment for rectal lymphogranuloma venereum. This study supports the continued recommendation of doxycycline 100 mg twice daily for 21 days as preferred treatment for rectal lymphogranuloma venereum in men who have sex with men.