Journal article
Age-Related Macular Degeneration and Mortality: A Systematic Review and Meta-Analysis
MB McGuinness, A Karahalios, RP Finger, RH Guymer, JA Simpson
Ophthalmic Epidemiology | TAYLOR & FRANCIS INC | Published : 2017
Abstract
Purpose: Age-related macular degeneration (AMD) is the leading cause of severe, irreversible vision loss in older adults. Evidence for an association between AMD and mortality remains inconclusive despite evidence for an association with cardiovascular and inflammatory diseases. We aim to compare all-cause, cardiovascular and cancer mortality between those with early or late AMD and control study participants. Methods: A protocol was registered at PROSPERO (CRD42015020622). A systematic search of Medline (Ovid), PubMed, and Embase (Ovid) was conducted on 6 June 2015. Reference lists from identified studies and four clinical trial registries were searched for additional studies. Participants ..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by an Australian Postgraduate Award and a studentship courtesy of the Victorian Centre for Biostatistics (NHMRC: Centre of Research Excellence grant 1035261) to MBM; the Lloyd and Kathleen Ansell Ophthalmology Foundation and the Mankiewicz-Zelkin Fellowship of the University of Melbourne to RPF; and CERA receives operational infrastructure support from the Victorian government. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.