Journal article
No Evidence for Genetic Contribution of Ocular Dominance: The Guangzhou Twin Eye Study
X Yan, N Congdon, J Zhang, Q Chen, X Guo, M He
Asia Pacific Journal of Ophthalmology | ASIA-PACIFIC ACAD OPHTHALMOLOGY-APAO | Published : 2014
Abstract
Purpose: The purpose of this study was to explore the heritability of ocular dominance in a classic twin study. Design: A classical twin study. Methods: Twins aged 7 to 19 years enrolled from the Guangzhou Twin Registry received comprehensive eye examinations. Ocular dominance was assessed by the “hole-in-the-card test” by trained optometrists. Zygosity of the participants was confirmed by genotyping in all same-sex twin pairs. The pairwise concordance rate was calculated as the main outcome. Results: After excluding 110 children with anisometropia of 2.0 diopters or greater and 24 children with alternating ocular dominance, a total of 941 twin pairs were identified in the analysis, includin..
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Awarded by Fundamental Research Funds for the Central Universities
Funding Acknowledgements
This study was supported by the National Natural Science Foundation of China (81125007), Fundamental Research Funds for the Central Universities, and Fundamental Research Funds for the State Key Laboratory.