Journal article
Enoxaparin for the prevention of preeclampsia and intrauterine growth restriction in women with a history: a randomized trial
KM Groom, LM McCowan, LK Mackay, AC Lee, JM Said, SC Kane, SP Walker, TE van Mens, NJ Hannan, S Tong, LW Chamley, PR Stone, C McLintock, A Lee, P Stone, C McLintock, W Ganzevoort, S Middeldorp
American Journal of Obstetrics and Gynecology | MOSBY-ELSEVIER | Published : 2017
Abstract
Background Preeclampsia and small-for-gestational-age pregnancy are major causes of maternal and perinatal morbidity and mortality. Women with a previous pregnancy affected by these conditions are at an increased risk of recurrence in a future pregnancy. Past trials evaluating the effect of low-molecular-weight heparin for the prevention of recurrence of preeclampsia and small-for-gestational-age pregnancy have shown conflicting results with high levels of heterogeneity displayed when trials were compared. Objective We sought to assess the effectiveness of enoxaparin in addition to high-risk care for the prevention of preeclampsia and small-for-gestational-age pregnancy in women with a histo..
View full abstractGrants
Awarded by University of Auckland Faculty Research Development
Awarded by Auckland District Health Board Charitable Trust
Awarded by Australasian Society of Thrombosis and Hemostasis Scientific and Education Trust
Awarded by University of Auckland School of Medicine Performance Based Research
Funding Acknowledgements
Supported by University of Auckland Faculty Research Development Fund (3625687/9803 and 3624720/9803); A+ Trust, Auckland District Health Board Charitable Trust (A+2011056); Australasian Society of Thrombosis and Hemostasis Scientific and Education Trust (3708366/9103); and the University of Auckland School of Medicine Performance Based Research Fund (71603/9450).