Obesity and type 2 diabetes have additive effects on left ventricular remodelling in normotensive patients-a cross sectional study
Kirstie A De Jong, Juliane K Czeczor, Smithamol Sithara, Kevin McEwen, Gary D Loopaschuk, Alan Appelbe, Kimberly Cukier, Mark Kotowicz, Sean L McGee
CARDIOVASCULAR DIABETOLOGY | BIOMED CENTRAL LTD | Published : 2017
BACKGROUND: It is unclear whether obesity and type 2 diabetes (T2D), either alone or in combination, induce left ventricular hypertrophy (LVH) independent of hypertension. In the current study, we provide clarity on this issue by rigorously analysing patient left ventricular (LV) structure via clinical indices and via LV geometric patterns (more commonly used in research settings). Importantly, our sample consisted of hypertensive patients that are routinely screened for LVH via echocardiography and normotensive patients that would normally be deemed low risk with no further action required. METHODS: This cross sectional study comprised a total of 353 Caucasian patients, grouped based on dia..View full abstract
Kirstie A. De Jong was supported by an Endeavour Research Fellowship and Australian Postgraduate Award, administered by the Australian Government, Department of Education and Training.