Journal article
The role of adenosine challenge in catheter ablation for atrial fibrillation: A systematic review and meta-analysis
AJA McLellan, S Kumar, C Smith, LH Ling, S Prabhu, JM Kalman, PM Kistler
International Journal of Cardiology | Published : 2017
Abstract
Aims Adenosine may unmask dormant PV conduction and facilitate consolidation of PV isolation. We performed a meta-analysis to determine the impact of adenosine administration on clinical outcomes in patients undergoing PVI. Methods References and electronic databases reporting AF ablation and adenosine following PVI were searched through to 22nd November 2015. The impact of adenosine on freedom from AF was assessed in twenty publications after radiofrequency ablation (RFA), and in four publications after cryoablation to achieve PVI. Relative risks were calculated and combined in a meta-analysis using random effects modeling. Results In patients undergoing RFA with adenosine challenge, there ..
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Awarded by St. Jude Medical
Funding Acknowledgements
Dr. McLellan was supported by a postdoctoral fellowship from the National Heart Foundation of Australia (Award ID 101322), a fellowship from the European Heart Rhythm Association - Asia Pacific Heart Rhythm Society, Endeavour Fellowship, and has received research support from St Jude Medical. Dr. Kumar is supported by a NHMRC early career fellowship. Dr. Ling is supported by a postdoctoral fellowship from the Australian National Heart Foundation. Professor's Kistler and Kalman are supported by a practitioner fellowship from the NHMRC. All other authors have reported that they have no financial relationships to disclose. Supported in part by the Victorian Government's Operational Infrastructure Support Program.