Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction

Kenji Onda; Stephen Tong; Sally Beard; Natalie Binder; Masanaga Muto; Sevvandi N Senadheera; Laura Parry; Mark Dilworth; Lewis Renshall; Fiona Brownfoot; Roxanne Hastie; Laura Tuohey; Kirsten Palmer; Toshihiko Hirano; Masahito Ikawa; Tu'uhevaha Kaitu'u-Lino; Natalie J Hannan

Journal article

Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction

Kenji Onda, Stephen Tong, Sally Beard, Natalie Binder, Masanaga Muto, Sevvandi N Senadheera, Laura Parry, Mark Dilworth, Lewis Renshall, Fiona Brownfoot, Roxanne Hastie, Laura Tuohey, Kirsten Palmer, Toshihiko Hirano, Masahito Ikawa, Tu'uhevaha Kaitu'u-Lino, Natalie J Hannan

Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2017

DOI: 10.1161/HYPERTENSIONAHA.116.08408

University of Melbourne Researchers

Tu'uhevaha Lino Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Roxanne Hastie Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Stephen Tong Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Fiona Brownfoot Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Natalie Hannan Author Obstetrics and Gynaecology Royal Women's Hospital/Mercy

Grants

Awarded by Medical Research Council

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) of Australia (S. Tong, N.J. Hannan, T. Kaitu'u-Lino, and K. Palmer) and the Austin Medical Research Foundation. S. Tong and T. K. Kaitu'u-Lino were supported by NHMRC Fellowships. N.J. Hannan was supported by a University of Melbourne CR Roper Fellowship.