Exposure to GDNF Enhances the Ability of Enteric Neural Progenitors to Generate an Enteric Nervous System

Role of kinesin binding protein and spontaneous activity in the development of enteric neurons

The nerve cells in the wall of the gut play an essential role in motility. Defects in the development of these nerve cells results in pediat..

Neural migration: Which cells advance and which stay behind?

This project aims to examine the neural crest cells that colonise the developing gut and to identify why some cells advance while others sta..

Manipulation of enteric neural stem cells for cell therapy to treat enteric neuropathies

Cell therapy offers great promise for the treatment of motility disorders due to defects in the nerve cells in the bowel. Patient-derived ce..

Development of nerve cells in the bowel

Gut motility requires enteric neurons, which are located in the gut wall. During development, enteric neurons arise from precursors in the b..

CELL THERAPY FOR ENTERIC NEUROPATHIES - THE ESSENTIAL NEXT STEPS

Gastrointestinal motility disorders caused by damage or diseased neurons in the gut wall ("enteric neuropathies) are some of the most clinic..