Journal article

Comparative and evolutionary analysis of grass pollen allergens using Brachypodium distachyon as a model system

A Sharma, N Sharma, P Bhalla, M Singh

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2017

Abstract

Comparative genomics have facilitated the mining of biological information from a genome sequence, through the detection of similarities and differences with genomes of closely or more distantly related species. By using such comparative approaches, knowledge can be transferred from the model to non-model organisms and insights can be gained in the structural and evolutionary patterns of specific genes. In the absence of sequenced genomes for allergenic grasses, this study was aimed at understanding the structure, organisation and expression profiles of grass pollen allergens using the genomic data from Brachypodium distachyon as it is phylogenetically related to the allergenic grasses. Comb..

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University of Melbourne Researchers

Grants

Awarded by Australian Research Council


Funding Acknowledgements

The research was funded by the University of Melbourne as a postgraduate scholarship for Akanksha Sharma. Financial support from the Australian Research Council (ARC DP0988972) is also gratefully acknowledged. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.