Journal article

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology

Kevin K Ogden, Wenjuan Chen, Sharon A Swanger, Miranda J McDaniel, Linlin Z Fan, Chun Hu, Anel Tankovic, Hirofumi Kusumoto, Gabrielle J Kosobucki, Anthony J Schulien, Zhuocheng Su, Joseph Pecha, Subhrajit Bhattacharya, Slave Petrovski, Adam E Cohen, Elias Aizenman, Stephen F Traynelis, Hongjie Yuan

PLOS Genetics | PUBLIC LIBRARY SCIENCE | Published : 2017

University of Melbourne Researchers

Grants

Awarded by Eunice Kennedy Shriver National Institute Of Child Health & Human Development (NICHD) of the National Institutes of Health (NIH)


Awarded by National Institute of Neurological Disorders and Stroke (NINDS) of the NIH


Awarded by National Center for Advancing Translational Sciences of the National Institutes of Health


Funding Acknowledgements

This work was supported by the Eunice Kennedy Shriver National Institute Of Child Health & Human Development (NICHD) of the National Institutes of Health (NIH) under award number R01HD082373 to HY, by the National Institute of Neurological Disorders and Stroke (NINDS) of the NIH under award number R01NS036654 to SFT, award number R24NS092989 to SFT,and award number R01NS043277 to EA, by the Xiangya Emory Medical Schools Visiting Student Program toWC, by Emory+Children's Pediatric Center Seed Grant Program to HY, and by the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR000454 to HY. LZF and AEC are supported by the Howard Hughes Medical Institute. SP is supported by the National Health and Medical Research Council of Australia. The funders had no rolein study design, data collection and analysis, decision to publish, or preparation of the manuscript.