Journal article

The evidence of benefits of exercise training in interstitial lung disease: A randomised controlled trial

LM Dowman, CF McDonald, CJ Hill, AL Lee, K Barker, C Boote, I Glaspole, NSL Goh, AM Southcott, AT Burge, R Gillies, A Martin, AE Holland

Thorax | BMJ PUBLISHING GROUP | Published : 2017

Abstract

Background Uncertainty exists regarding the clinical relevance of exercise training across the range of interstitial lung diseases (ILDs). Objective To establish the impact of exercise training in patients with ILDs of differing aetiology and severity. Methods 142 participants with ILD (61 idiopathic pulmonary fibrosis (IPF), 22 asbestosis, 23 connective tissue disease-related ILD (CTD-ILD) and 36 with other aetiologies) were randomised to either 8 weeks of supervised exercise training or usual care. Six-minute walk distance (6MWD), Chronic Respiratory Disease Questionnaire (CRDQ), St George Respiratory Questionnaire IPF-specific version (SGRQ-I) and modified Medical Research Council dyspnoe..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

LMD received a National Health and Medical Research Council postgraduate scholarship (Grant ID: GNT1017802) and this trial received grant funding from the Pulmonary Fibrosis Foundation/American Thoracic Society Foundation, Institute for Breathing and Sleep and Eirene Lucas Foundation.